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The validity of collecting APACHE II data from retrospective chart review has not, to our knowledge, been validated (for example, accurate assessment of Glasgow coma score may be very difficult).
Although many of the questionnaires commonly used in clinical trials have been validated, for example, the FACT (Cella et al, 1993) and EORTC QLQ (Sprangers et al, 1993) questionnaires, these do not explore the impact of each specific symptom on daily activities (Steineck et al, 2002).
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Provisional evidence leading to a drug's approval may later be validated; for example, one FDA review showed that most anticancer drugs approved using the accelerated approval pathway are eventually confirmed as safe and effective on the basis of successful post-approval studies.
It has been validated for Drosophila and we present examples of its power to address biological questions.
For example, the Eichner index has been validated for an elderly Japanese population with respect to chewing ability [ 17].
These assays were validated for placental samples.
The use of syndromic surveillance has been validated previously, for example the exploitation of respiratory data [ 20].
DragHome has been validated at examples for which crystal structures are available: structurally distinct thrombin inhibitors were docked onto models of thrombin generated from serine proteases of 28 to 40%% sequence identity, yielding ligand binding modes with an average RMS deviation of 1.4 Å. Mostly the near-native solutions are ranked best.
2 Typically, the model is validated internally (for example, using bootstrapping 7 in box 2) or externally using patient data not used for model development (box 1).
It can be easily validated, for example the stability has a tendency to deteriorate when the penetration of DGs increases or the grid gets weaker for application in engineering.
A number of prediction models with relatively similar components have been validated in other cohorts, for example, the PROCAM score (61), the ARIC clinical model plus glucose (52, 57, 58), and the Rancho Bernardo model (47, 66).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com