It has been validated for assessing pain in children with cognitive impairment, in young children [ 29] and in children with postoperative pain [ 27], and in comparison with children's self report of pain [ 30].
Relationships between regional cortical thickness or volume (measured with an unbiased and automated data analysis system) and cognitive task performance have been validated for a range of tasks [26].
The SIRS-2 is widely used for the identification of malingering in forensic psychiatry [ 10], and it has been validated for the detection of feigning specific disorders or cognitive deficits among psychiatric populations and adolescent offenders [ 11- 13].
The scale has been developed for use in geriatric and vulnerable samples and offers a simple, dichotomous response format; it has also been validated for use with persons with mild-to-moderate cognitive impairment [ 50– 50].
The procedure has previously been validated for hippocampal volume measurements in elderly subjects, including mild cognitive impairment and Alzheimer's disease patients (Hsu et al., 2002).
NeuroTrax has been validated for use as an assessment for the detection of possible mild cognitive impairment [37], [38].
The FFSS has been validated for use in PBC, and quantifies fatigue in a physical, social and cognitive domain [ 6, 10].
The Anticholinergic Activity Scale (AAS) by Ehrt et al., and Anticholinergic Loading Scale (ACL) by Sittironnarit et al. were validated for only cognitive outcomes.
A simple 10-item Summary scale, together with scales measuring the physical and cognitive components of fatigue, were validated for MS fatigue.
Simulator performance shows medium to strong correlations with many on-road driving performance measures as well as to cognitive and physiological measures, however simulators need to be validated for each new setting [32].
