Sentence examples for been validated clinically as from inspiring English sources

Deregulated expression of PTKs is responsible for tumor development and progression, including hyperproliferation, angiogenesis, invasion and chemotherapy resistance, and have been validated clinically as promising new targets in cancer therapy [2], [4], [5].

Gene expression profiling of migratory glioma cells induced to disperse in vitro affords discovery of genomic signatures; selected candidates were validated clinically at the transcriptional and translational levels as well as through functional assays thereby underscoring the fidelity of the discovery algorithm.

However, the superior efficacy has not been validated clinically (Till et al., 2012).

These predictions have not been validated clinically.

The results of the model should be validated clinically.

Should the RTA classifier be validated clinically, this algorithm is amenable to a user-friendly implementation.

The most prominent contributor to the migratory phenotype was validated clinically and functionally by siRNA.

Unlike other solid tumors, no oncogenic addiction loops have been validated as clinically actionable targets in HCC.

However, this did not work in all cases and additionally has not been validated as the most clinically relevant classification.

The Prosigna assay has been validated as a prognosticator in clinically low-risk, postmenopausal patients with ER-positive early-stage breast cancer treated with endocrine therapy [ 16– 16].

Most of the 12 proteins have been associated generally with cancer biology, some have been identified as candidate lung cancer biomarkers, none have been validated as lung cancer biomarkers, and none are used clinically [33], [34].