Sentence examples for been used in tumor from inspiring English sources

Spheroids as 3-D cell constructs have been used in tumor research for a long time.

Since tenascin-C is highly overexpressed in tumor stroma antibodies against tenascin-C have been used in tumor diagnosis and therapy.

Thirdly, different methodologies may have been used in tumor archiving and RNA preparation.

Due to the complex nature of cancers, a variety of gene-based therapeutic strategies have been used in tumor gene therapy.

While multiple groups have used this elegant system to study mitochondrial function in cultured cells (see reviews [ 4, 75]), only recently have these cybrids been used in tumor xenografts [ 64].

Several negative regulators of angiogenesis, such as angiostatin, endostatin, vasostatin, modulators of vascular endothelial growth factor activity (sFLT-1), and cytokines/chemokines with marked anti-endothelial activity (IL-12, IFN-α, CXCL10, and others) [44], have been used in tumor therapy.

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Autologous DCs can be used in tumor vaccination (1) pulsed with synthetic peptide derived from the known tumor antigens [ 131], tumor cell lysates [ 132], or apoptotic tumor cells [ 133], (2) transfected with whole-tumor mRNA [ 134] or with mRNA or cDNA of a specific antigen [ 135] and (3) fused with tumor cells to induce antigen-specific polyclonal CTL responses [ 136].

Hierarchical cluster analysis (HCA) is an unsupervised agglomerative clustering algorithm that is widely used in the analysis of gene expression data [16] and is beginning to be used in tumor analyses to cluster anatomic structures with primary tumor involvement into several groups.

Contrary to this, there are few pharmaceuticals which are used in tumor-specific therapies that were found insufficient to check aberrant signaling pathways in brain tumors [ 24].

Currently, the biomedical imaging modalities that have been used in evaluating tumor angiogenesis include MRI, positron emission tomography, ultrasound, optical imaging, and computed tomography [30], [43] [45].