The latter, i.e. the upper limit, however mainly depends on the level of investigation, the considered compound, the lowest measured concentration and/or the achieved compound-specific detection limit and therefore cannot be unequivocally defined.
For the remaining six BMVs (BMV2 7), the integration sites could not be unequivocally defined by direct comparison of provirus-containing and provirus-free strains, due to unavailability of the genomic sequences for the latter group.
While the category of 'reactive' hornets is unequivocally defined, the category of 'nonreactive' hornets remained to be crucial because of its dependence on gross subjective manual criterions, which did not allow deciding in detail about any residual pattern of reactivity of the hornets to e shimmering.
However, the role of MBL and the lectin pathway cannot be unequivocally defined, as published data points to opposite and sometimes confusing conclusions (Table 1).
Despite that M1c cannot be unequivocally defined by transition 16185, it can be stated that M1c is an overwhelmingly Northwest African clade which spreads to the Mediterranean and West sub-Saharan Africa areas.
Most important, a very clear dissimilarity from the control group indicated that the indomethacin-treated animals had been exposed to a toxic compound, although the mode of toxicity could not be unequivocally defined.
Historically, retrospective cohort designs are used when the at-risk population can be defined, such as at a "church" picnic (CDC, 1995); a case-control approach is used when the at-risk population cannot be unequivocally defined and/or enumerated (CDC, 2007).
Coronary atherosclerosis is, therefore, not unequivocally defined by CCS ≥400 but evidence suggests that this cut-off value defines clinical significant disease in diabetic patients with proteinuria [ 13].
In this position paper, we attempt to define what we have learned during these past 10 years, which questions have been unequivocally answered, and which novel questions arose.
