And he said the country's ability to lead and inspire around the globe was being undermined by problems at home.
However, the evidence is undermined by problems in the design and conduct of the trials, and as all studies used slightly different variants of the bundle it is difficult to predict whether a comparable reduction in risk would be achievable in Australia.
Mancini claimed his squad had been undermined by injury problems as he said: "This season we had some problems with players injured.
Secretary of State John Kerry, after talks with his Russian counterpart, Sergey V. Lavrov, said an internationally brokered cease-fire in Syria had been undermined by two problems: bombings by the Syrian government and attacks by the Nusra Front.
But observers from the Organisation for Security and Cooperation in Europe (OSCE) said earlier on Monday the ballot's integrity had been undermined by "significant problems", especially during the counting of the votes.
Objectivity has been undermined by the measurement problem in quantum physics, which must account for how the observer actually changes or influences the thing he observes.
But confidence has been undermined by a range of problems.
Keane's argument for this international break, however, has been undermined by McCarthy's fitness problems, Coleman's availability and the fact another of Everton's Irish contingent, Darron Gibson, played 70 minutes at Celtic Park despite being short of match fitness as he recovers from a serious knee injury suffered on international duty last year.
Plans to convert massive amounts of used cooking oil and household trash to liquid fuel, meanwhile, have long been undermined by technological and environmental problems.
But McLaren have been undermined by pit lane mistakes early in the season, followed by problems with reliability.
