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Very few of the human-specific insertions were found in regions thought to have been under positive selection when analyzed using population genetic methods aimed at detecting the signatures of selective sweeps.
It looks as though women's old age has been under positive selection.
Recent analyses of human genomic data suggest that many genes have been under positive selection in recent history (e.g., Nielsen et al. 2005; Voight et al. 2006; Williamson et al. 2007; Sabeti et al. 2007), including some involved in taste and smell, lactose and sucrose digestion, and disease resistance.
In the NWMs, regions located in N-terminal and ectodomain have been under positive selection (Figure 5C).
The EHH values of core haplotype (3), AGA, decayed more slowly than the other core haplotypes, indicating haplotype (3) may have been under positive selection.
To test whether this haplotype might have been under positive selection in these populations, we simulated the population demography (Figure 7B).
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Position 235 has a high probability (0.933) of being under positive selection as well.
Three positions in V2, C2, and V3, were found to be under positive selection across subjects.
This result indicates that complex epistatic interactions may be under positive selection within these heterogeneous environments.
The sparse outer boundaries of these regions are less highly conserved and are under positive selection.
As shown in Table 1, 10 sites were found to be under positive selection.
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