Sentence examples for been under negative selection from inspiring English sources

The extended TPX2 domain thus seems to have been under negative selection only.

Phylogenetic footprinting approaches have originally focussed on the identification of regions that have been under negative selection throughout a given phylum [ 26].

At the individual codon level, we found 99 residues were under negative selection in MYB genes without a single positively selected residue.

Substitutions that deleteriously affect the affinity, specificity and selectivity of a beneficial motif will generally be under negative selection and will fail to spread through the population.

The authors also found a correlation between genes predicted to be under negative selection and genes implicated in certain hereditary diseases.

For example, among the genes the researchers predicted to be under negative selection are those involved in muscular dystrophy and in Usher syndrome, the most common cause of congenital blindness and deafness in developed countries.

They claim that the likely reason that these virulence factors are under negative selection is that they lead to immune evasion (the immune system targets the virulence factors).

Sebat et al.[12] suggests that CNVs might be under negative selection.

It is clear that both CHR-O and N-CHR homologous groups are under negative selection.

Two of the site-specific methods also yielded evidence of a single codon, at position 99, being under negative selection.

Besides, even though all the sites in a protein are under negative selection, various negative selection pressures still may appear in different domains in a protein.