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Individual DHSs within small regions of the genome (10 20 kb) have been traditionally identified using Southern blot analysis [ 6].
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A disadvantage of array CGH is that it cannot detect LOH, which has traditionally been identified using methods involving microsatellites and restriction fragment length polymorphisms (RFLPs) that are not suitable for large-scale analyses (see [42]).
A recent example is provided by the dengue vector mosquito, Aedes aegypti, whose source populations have traditionally been identified using mtDNA markers coupled with microsatellites (Endersby et al. 2011; Brown et al. 2014).
Traditionally, the connections a neuron makes have been identified using techniques such as electrophysiological recordings, histochemical techniques, anterograde or retrograde tracers, and functional imaging.
Traditionally, C. elegans mutations are identified using a combination of multi-point or deficiency mapping by crossing the mutant of interest to marker strains.
Traditionally, these lightning strike points are identified using the rolling sphere method, through an empirical correlation with the prospective peak return stroke current.
Substorm onsets are also traditionally identified by using negative bays, positive bays, and Pi2 pulsations in ground magnetic field data.
Standardized drought indices have been traditionally used to identify and assess droughts because of their simplicity and flexibility to compare the departure from normal conditions across regions at different timescales.
These chromosomal rearrangements have been traditionally used to identify tumour plasma cells.
Although light and electron microscopy have been traditionally used to identify microalgae, small subunit ribosomal RNA gene (16S or 18S rDNA) sequences are considered as an ideal tool in the identification of microorganisms, including microalgae [ 30- 32].
Impaired fasting glucose (IFG) (100 125 mg/dL) has been traditionally used for identifying persons at high risk for the subsequent development of diabetes in the U.S. Recent guidelines have additionally endorsed the use of HbA1c 5.7–6.4% to identify those at risk (1).
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