Suggestions(2)
Exact(2)
Several of these have been tested in thyroid cancer models in vitro.
Lexatumumab (HGS-ETR2) is a fully humanized agonistic monoclonal antibody that specifically activates the TRAIL-R2 and has never been tested in thyroid cancer in any capacity.
Similar(55)
Although these combinations have not been tested in the setting of thyroid cancer, they have been evaluated in other diseases.
Local deiodinase expression has not been tested in adipose tissue during inflammation, so thyroid hormone availability is not known in this compartment.
The recent explosion of multitargeted inhibitors in medical oncology has resulted in many of them being tested in refractory thyroid cancer.
Harvests of samples that induced cytopathic effect (CPE) in primary bovine thyroid (BTY) cells were tested in antigen ELISA (Ag-ELISA) and in 5'UTR-targeted real time RT-PCR (5'UTR RT-qPCR).
This hypothesis was tested in four natural experiments: human growth and development, thyroid dysfunction, chronic renal failure, and hibernation.
Combination therapy has not yet been tested for activity in thyroid cancer in vitro or in vivo.
Comparison of a genomic region extending for about 100 kb at the 5'-flanking region of the mouse and human Pax8 gene revealed several conserved regions that were tested for enhancer activity in thyroid and non-thyroid cells.
The complete nucleotide sequence and predicted amino-acid sequence of the heavy- and light-chain variable region of scFv-C1 clone is shown in Figure 3B, and complete sequencing analysis in Supplementary File 2. The scFv monoclonal antibody immunoreactivity was tested on the 229 thyroid samples included in the TMA.
In addition, patients were tested for Cushing syndrome and thyroid dysfunction (6).
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Justyna Jupowicz-Kozak
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