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Uncertainty about possible harmful outcomes can be assumed to be much greater when the genome alteration is accidental and harm may go unnoticed for long than when interventions are targeted and have been tested in model systems, and mathematical predictions can be made.
While most have only been tested in model organisms, literally hundreds of geroprotectors now exist [ 10- 15].
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Peroxisome-proliferator activated receptor (PPAR -δ agonists have never been tested in models of sugar-induced metabolic abnormalities.
New complexes were tested in model RCM, enyne and CM reactions.
Catalytic activity of such immobilized palladium complexes was tested in model Mizoroki–Heck reactions.
Smart grids are being tested in model regions in Austria at the moment, e.g. in Salzburg [53].
After being tested in model species, SDNs are starting to be used to introduce new genetic variability in crops.
The value of these targets for new treatment strategies is being tested in model systems and, once safety and efficacy are assured, in human trials.
Ti modified-mesoporous carbon was used as support of the iridium nanoparticles, in order to prepare a catalyst to be tested in model hydrotreating reactions.
Patient-specific covariates were tested in model development.
Saturable and first-order rate of formation of dFdCTP were tested in model development.
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CEO of Professional Science Editing for Scientists @ prosciediting.com