Such validation can be achieved by two complementary strategies: either a 'bottom-up' approach in which candidate oncogenic mutations are systematically engineered into normal wild-type tissue, or a 'top-down' approach in which tumor tissue is exposed to genetically manipulated oncogene candidates or therapeutics.
In a campaign that appears to be systematically engineered to disqualify him from consideration for any position of responsibility, nothing comes close to his pronouncements on nuclear weapons.
The editors developed this integrated book with three aims: to explain self-organisation concepts and principles, using clear definitions and a strong theoretical background; to examine how self-organising behaviour can be modelled, analysed and systematically engineered into agent behaviour; and to assess the types of problems that can be solved using self-organising multiagent systems.
This study showed how the wool fibre can be systematically reverse engineered into its constituent components, with minimal to no chemical or physical change to the desired component.
Experts estimate China has as many "cyber jedis" as the US has engineers, and some of them, with backing from the state, have been systematically hacking into and stealing from governments and companies in the west, taking defence secrets, compromising computer systems, and scanning energy and water plants for potential vulnerabilities.
This is something that has been systematically fed into the bloodstream.
Also included is a considerable amount of material from existing literature which has not been systematically organized into a monograph.
Only recently has training in disaster preparedness and response been systematically incorporated into the curricula of mental health disciplines.
"The Silver Ghost was the first systematically engineered car with very, very high-quality standards, and the first upper-class automobile embraced as a dignified way to travel," said Tony Lewin, who covers the company for Automotive News Europe.
The mechanisms that regulate myosin function and the supramolecular structures into which myosin incorporates have not been systematically characterized.
