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A number of different structures have been synthesized to optimize the rotation process and to explore the limits of the system.
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A series of POSS-containing resists with varying POSS contents were synthesized to optimize the dry etch resistance and selectivity.
Firstly, two FPENs with different repeating units (homo-FPEN and co-FPEN) in backbone were synthesized to optimize the FRET efficiency.
As newer targets for siRNA are identified and novel lipids are synthesized to optimize their in vivo efficiency, concomitant development of bio-physical methodologies that can improve understanding of the assembly and stability of these complex systems is critical.
The fact that only water and ethanol soluble compounds were used in this study (Noel et al., 2008) is quite important: in drug discovery programs, compounds are primarily synthesized to optimize their pharmacological activity, often resulting in highly lipophilic compounds with poor water solubility.
In the recent years, nanomedicine has been developed and many nanostructures have been designed and synthesized to optimize the tissue-engineered based treatment strategies.
A series of lipidated vancomycin analogues 1 bearing disulfide bonds within their lipid chains was designed and synthesized to optimize their ADME profiles while retaining antibacterial potency.
Novel isoxazoline amide benzoxaboroles were designed and synthesized to optimize the ectoparasiticide activity of this chemistry series against ticks and fleas.
A series of di-indolinone derivatives was designed and synthesized to optimize our lead compounds basing on molecular docking study as PTP1B inhibitors.
With variation of reaction conditions/factors, various grades of crosslinked hydrogels/nanocomposites have been synthesized and optimized on the basis of lower % swelling and higher % crosslinking.
A series of ferrocenyl derivatives (1, 2, 3 and 4) containing phenol group, chemosensors for anions, have been synthesized and optimized.
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