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A possible role for BAS dysregulation in the bipolar spectrum in general and in patients with bipolar I specifically has been supported in several studies using the self-report BIS/BAS scale (Carver and White 1994).
The validity, feasibility, and ability to detect changes in depressive symptoms has been supported in several studies [ 27- 29].
Although the validity of ACIC has previously been supported in several studies, these have varied methodologically with regard to the respondents who completed the measure.
In contrast, this function in light attenuation has not been supported in several species (Woodall et al. 1998; Esteban et al. 2008; Nikiforou and Manetas 2010) in which anthocyanic tissues are more sensitive to photoinhibition than green ones.
Its effectiveness has been supported in several RCTs, reporting significant improvements in pain and disability compared to 'routine' physiotherapy (i.e. advice/education, passive mobilisation/manipulation)[ 10] and GP management [ 11], and it has been shown to be cost effective[ 11].
The supervised exercise programme is based on the "Back to Fitness" class, whose effectiveness has been supported in several RCTs, reporting significant improvements in pain and disability compared to 'routine' physiotherapy [ 35] and GP management [ 36], with comparable effects to spinal manipulative therapy [ 37].
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The case for height-for-age, as a marker for long-term health outcome is supported in several studies [11 13] which assert an association between taller height and better health, better cognitive outcomes, greater earning ability, and higher probability of being employed.
Construct validity of the IRI scales was supported in several studies [2].
This is supported in several studies [ 12– 12].
A role for DNA methylation in regulating fibroblast phenotype during disease progression is supported in several studies.
Known-groups validity of the EQ-5D index score and VAS was supported in several group comparisons (Table 7).
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