Lmx1a has previously been suggested to regulate neurogenesis in an indirect manner through regulation of the downstream gene Msx1 (Lin et al., 2009; Andersson et al., 2006b).
Moreover, the Wnt pathway has also been suggested to regulate prominin-1 expression, 46 concordantly with its central regulation for LGR5 expression in intestinal crypts.
Other primarily cytoplasmic signaling proteins have been suggested to regulate mitochondrial ROS production, both positively and negatively [66 68].
The H19 noncoding RNA has been suggested to regulate an imprinted gene network [79].
Thus, CAR has been suggested to regulate a cellular signal leading to cell growth and death.
H2O2 has been suggested to regulate KATP channel activity or KATP channel-related cellular function in several cell types.
Similarly, phosphorylation of dynamin has been suggested to regulate the rate of synaptic vesicle endocytosis (SVE) [40].
For example hnRNAP, Lin28, and KSRP have been suggested to regulate Microprocessor activity on specific miRNAs [21], [22], [23], [24].
In fact, the cGMP pathway has previously been suggested to regulate DAF-28 signaling during dauer formation (Figure S1; [18]).
Several transcription factors have been suggested to regulate phenotypic modulation of SMCs but the decisive mechanisms remain unknown.
Sh3gl3 is an intracellular protein whose homologs have been suggested to regulate endocytosis and intracellular membrane trafficking [62].
