This approach, although still in the beginning, is promising, and, if standardized, is suggested to complement the conventional proteomics approach as it reflects the cancer-related protease activity.
We and others have demonstrated the presence of CFH in atherosclerotic lesions [75,97,98] and CFH has been suggested to inhibit complement activation during atherogenesis [99].
ELISA testing is not routinely used in bovine TB control programs mainly due to a reduced sensitivity [ 26], although it has been suggested to be used as a complement to the tuberculin test, especially for the detection of anergic tuberculous cattle [ 27, 28].
Although nanomedicine-mediated triggering of complement activation has been suggested to be a significant contributing factor to these adverse events, complement activation may still proceed in non-responders.
Myelin staining for complement proteins has been suggested to be a non-specific feature [ 12]; however, using double immunolabelling we found complement markers co-localized in areas of degenerating myelin and damaged axons in MS sections, implicating complement in axonal and myelin injury in and around active and chronic plaques.
Complement activation has been suggested to play a role in the development of secondary injuries following traumatic brain injury (TBI).
Recommendations are suggested to improve and complement these tools in future use.
Thus, it is suggested to conduct studies that complement these issues (method of BP measurement, normotensive control group, and sample size).
Artificial gravity (AG) exposure is suggested to counteract health deconditioning, theoretically complementing exercise during space habitations.
Both human HSP60 and PAD4I are found to be expressed in the synovium, and PAD4I is suggested to form complexes that activate complement proteins, thereby giving rise to the observed correlation between the detection of the protein and the intensity of tissue inflammation in RA [ 53].
