Sentence examples for been suggested that persistent from inspiring English sources

It has been suggested that persistent hypothalamic activation could be the factor that contributes to generate a central permissive state which predisposes to activation of the trigeminal system, mediating pain, and of the parasympathetic reflex, producing the autonomic symptoms [52].

It has been suggested that persistent hyperarousal at autonomous, emotional, cognitive, or neurobiological levels may be the decisive factor in the development and persistence of chronic primary insomnia [ 26– 28].

It has been suggested that persistent antigen load secondary to chronic infection and high viral replication rate lead to excessive formation of immunocomplexes, and these circulating immunocomplexes deposited in intermediate and small-sized vessels initiate vasculitic processes [ 28, 29].

Although ERKs are thought to play a key role in cell proliferation, it has been suggested that persistent activation of ERKs might result in cell cycle arrest and differentiation in PC12 cells, or cell growth inhibition and apoptosis in normal rat hepatocytes and several human tumor cell lines [ 65].

For cases with older onset (aged 5 years and over) it was suggested that persistent infection may have been established in utero or early infancy and, now, formal testing of appropriate space-time interactions provide indirect confirmation of this (P = 0.0002).

It has therefore been suggested that a persistent turnover of glucose to lactate even under aerobic conditions (Warburg effect) is an efficient means to increase biomass production and maintain high proliferation rates [ 14].

It has been suggested that excessive and persistent postoperative pain may be a precursor to chronic pain.

As a very provocative theory it has been suggested that this subpopulation of persistent DTC may also be seen as cancer stem cells since they are dormant but have the ability to regrow following treatment [ 32, 33].

Very recently it has been suggested that the transient, resurgent and persistent phases of the sodium current in cerebellar granule cells are all interlinked through the β4 subunit (Bant and Raman, 2010).

Also, it has been suggested that, in the presence of persistent experimental or chronic low back pain, subjects need to adapt their motor control strategies in order to limit exacerbation of pain symptoms[ 9, 19].

However, it has been suggested that in epidemiological studies investigating persistent organochlorine pollutant (POP -toxicity, other POP -toxicitycurring simultaneother may carry an increased risk of effects, which may obscure a clear interpollutantsoccurringle of POP toxicity.