This finding confirms what has been suggested in previously published randomized controlled trials in a "real life" setting.
The benefit of adding a second-generation antipsychotic, such as risperidone, quetiapine, or olanzapine for the treatment of PTSD in combination with a primary antidepressant has been suggested in numerous small studies, including a few randomized controlled trials [ 27- 30].
However, the usefulness of hydrating lower risk patients for CIN (based on the absence of diabetes mellitus, age > 65 year, sCr >1.4 mg/dl) to prevent the incidence of CIN was suggested in a non-randomized controlled trial [ 25].
Although prone positioning has been suggested to be lung protective, randomized multicentre trials were unable to demonstrate improved survival in patients with ARDS with prone positioning [ 2, 3].
It has been suggested that the vitamin E doses in the randomized trials were too low to show any effect (32), and high doses in some trials increased mortality (5).
Recently, it has been suggested that the progression of DSPN in the placebo group within the setting of a randomized clinical trial over 4-year period was slow.
It has been suggested that the ideal situation for data collection is to collect economic data along side health outcomes in a randomized pragmatic trial [ 10].
Finally, the CONSORT criteria was suggested primarily for randomized controlled trials, which in this particular case only accounted for about 10% of the study designs in conference abstracts.
In addition, the CONSORT criteria were suggested primarily for randomized-controlled trials which took only about 2-72-7% studesignsgns in conference abstracts.
Sleazy drive-ins were suggested.
