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In recent years, several mathematical concepts have been successfully explored in the computer science domain as a basis for finding original solutions for complex problems related to knowledge engineering, data mining, and information retrieval.
The use of poly (ethyleneglycol)/poly (acrylate)/salt system has been successfully explored in the purification of protein and plasmid DNA.
Indeed, such therapeutic options have been successfully explored in a murine model of hepatocellular carcinoma [ 56].
Antiapoptotic agents have been successfully explored in models of diseases affecting the central nervous system, liver and kidneys [ 55- 57].
In conclusion, a lot has been learned on the structure and function of the LysM domain, and this knowledge has been successfully explored in various potential applications.
Because an earlier version of such data had been successfully explored in concentrating on benign with damaging missense variants [ 10], we followed this approach but used the Rate4Site tool [ 22] for higher accuracy of conservation estimation.
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Human mutations that introduce premature stop codons, leading to protein truncation, could in theory be treatable using readthrough-inducing drugs (Zingman et al., 2007), a strategy that can also be successfully explored in models.
Numerous studies have shown that maturation is essential for HIV-1 infectivity because genetic mutations either in Gag or PR that inhibit maturation lead to the production of non-infectious HIV-1 particles 1, 2, 3, 4, 5, 6, 7. Pharmacological intervention in HIV-1 maturation has been successfully explored, resulting in the discovery and development of two classes of HIV-1 inhibitors.
Carbon nanotubes, due to their natural photoluminescence in the tissue-penetrating near-infrared region, have been successfully explored as potential imaging tools [7].
Such a possibility has recently been successfully explored [41] with very promising preliminary results.
So far, N. benthamiana has been successfully explored as a model for expression of therapeutic proteins, such as antibodies [20].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com