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Monoclonal antibodies have been successfully engineered as approved therapeutics.
The laboratory strain of murine cytomegalovirus (MCMV), K181, has been successfully engineered as a vaccine expressing murine zona pellucida 3 (mZP3) for viral vectored immunocontraception (VVIC) in mice.
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Of the remaining 14 genes, 6 proved difficult to amplify or clone, but 8 were successfully engineered as C-terminal fusions with a yellow fluorescent protein (YFP) reporter.
In the last decade various traits such as biotic stress resistance, quality and storage life have been successfully engineered into vegetable crops and some of them have been commercialized.
Synthetic functional RNAs, such as in vitro selected small-molecule-binding aptamers, have also been successfully engineered to produce predictable and controllable gene expression.
To their surprise, 99.5 per cent of offspring had been successfully engineered, Professor James said.
Many protein fragments have been successfully engineered using multiple display platforms.
There have been examples where each of these reasons has been successfully engineered.
In addition, viable whole genome recombinants between different prokaryotes have also been successfully engineered [ 35].
PHB has been successfully engineered in a number of plant species [ 9] and has potential applications not only as a bio-plastic but also for the manufacture of chemicals and improved animal feed [ 9– 13].
This gene has been successfully engineered in CHO cells to improve productivity in the past (Tigges and Fussenegger, 2006).
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