These results suggest that the risk of cigarette smoking resulting in adenocarcinoma of the lung has increased substantially over the same time interval during which there has been substantial changes in the characteristics of the cigarettes smoked, but the risk of developing squamous cell carcinoma has remained unchanged.
In recent decades, there have been substantial changes in mortality from urologic cancers in Europe.
Since the 1990s, there have been substantial changes in the composition of immigrant groups to arrive in Spain.
By running programs such as education, provision of shade in open spaces, rescheduling of work and sports activities, removal of sales taxes from approved sunscreens, and provision of cheap sunscreens, there have been substantial changes in knowledge, attitudes, and beliefs about sunlight and suntans, as well as an increase in sun protection behavior in Australia.
Second, differences between the NDVI of protected areas and that of their surroundings have been widely maintained over a 25 year period, during which the global human population has increased by ∼45% [63] and there have been substantial changes in patterns of global land cover [4], [64].
There have been substantial changes in the treatment of DLBCL in the past two decades.
Although there has been substantial change in the tech community over the past decade, early-stage venture capital operations and processes are for the most part the same as they were twenty years ago.
A major concern is that the supply of electricity might exceed demand for about 1,000 hours each year by 2020 unless there are substantial changes in the way electricity is managed in Denmark, Mr. Birkebaek said.
Along with the climatic shifts documented by the paleosols there also are substantial changes in alluvial architecture and paleotopography.
The question arises if the experiments obtained with these columns are scalable, because there are substantial changes in extra column volume when going from a very small scale to a benchtop column.
Although there were substantial changes in society and political structures, the break with Antiquity was not complete.
