Nasal trigeminal TRPA1 as well as TRPM8 stimulation had never been studied regarding modulation of the cough reflex in humans.
In addition, the glial cells of trigeminal ganglion, particularly the satellite glial cell, were studied to understand a possible relation.
In order to provide a broader basis for the analysis of the developing trigeminal placode, 14 other serially sectioned embryos were studied (phases 2 4, Table 1).
It has been widely studied in patients with orofacial pains or trigeminal neuropathy and, in combination with the IAN conduction study, showed sensitivity (59%) and specificity (100%) values very similar to those we found in our patients.
Few studies have been conducted in trigeminal system.
Orexin 1 receptor (OX1R) has been reported in trigeminal nucleus caudalis.
Indeed, the diagnostic accuracy has always been a problem in studies in trigeminal neuralgia.Adverse events may cause withdrawal from treatment.
Artemin exerts its roles in intracellular signaling pathways through the receptor complex of ret and GFRa3, and recent studies suggest that GFRa3 was present in trigeminal afferents that innervate the dura [9, 11].
Latency is established in trigeminal ganglia and lymphocytes.
TRPV4 mRNA is expressed in trigeminal ganglion neurons, and functional effects of TRPV4 activation can be measured in trigeminal neurons in vitro.
