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This program, which has been studied in models run by geriatricians with the assistance of a multidisciplinary team, includes a comprehensive medical and nursing admission assessment focusing on the patient's premorbid function, cognition, comorbidities, and risks is followed by a comprehensive care plan design.
Many genes involved in the regulation of myofibroblast differentiation have been studied in models of in-vitro differentiation [ 17- 20].
The anti-inflammatory and neuroprotective roles of minocycline have been studied in models of peripheral and central neuropathic pain.
Bumetanide, a more potent and specific antagonist of NKCC1 than furosemide, has also been studied in models of animal seizures.
The effects of GLP-1R agonists have also been studied in models of MI (ischemia with or without reperfusion) and heart failure (HF).
Although the role of miR-34a as a potential therapeutic in vivo has been studied in models of colon cancer [ 13], lung cancer [ 26] and glioblastoma[ 25] to date the ability of miR-34a to inhibit neuroblastoma cell growth has thus far only been investigated in vitro.
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"Some circadian rhythm genes we identified have been studied in model organisms, but much less so in humans," said David Hinds, Ph.D, a Principal Scientist and Statistical Geneticist at 23andMe.
Colloid retention in soils has mainly been studied in model homogeneous porous media, and during single irrigation events.
The role of key environmental factors in adaptation of spore-forming and non-spore-forming transgenic microorganisms (TM) have been studied in model ecosystems.
Genes in the cellulose synthase superfamily have been studied in model plants, such as rice [ 18] and Arabidopsis[ 17].
However, PSEN mutations have mostly been studied in model systems that do not accurately refl ect the genetic background in FAD patients.
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