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This strategy has not been studied for efficacy with respect to sickness absence but has been applied as 'return to work' intervention [ 47].
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Therefore zolpidem, a short-acting GABAAR modulator with selectivity for the type-I (ω1) benzodiazepine receptor, was studied for efficacy in altering rat sleep architecture as determined by electrocorticogram (ECoG) and electromyogram (EMG) activity over a 7-day sub-chronic administration period.
To overcome its limitations, several lipophilic prodrugs including 4- N -stearoyl Gem (GemC18) have been studied for their efficacy over Gem.
Many of these agents have already been studied for their efficacy against FHV-1 [ 15, 16].
First, a biologic agent, efalizumab, which had been studied for possible efficacy in severe AD, has been removed from the market for safety concerns.
In the last 10 years, the catechol- O-methyltransferase (COMT) inhibitor tolcapone has been studied for its efficacy as an adjunctive treatment to levodopa plus a dopa decarboxylase inhibitor.
Blocking of MMP activity has been studied for potential therapeutic efficacy in controlling such pathologic processes.
Very few, however, have actually been studied for evidence of their efficacy.
It is important to note that other pharmacologic agents have been studied for delirium prevention, but demonstrating efficacy for delirium prevention has been elusive [ 37].
In the second part of this paper, the NSFDM is studied for its efficacy in application to nonlinear scalar hyperbolic conservation laws.
Chwalek noted that skin care and beauty products are studied for their efficacy on an individual basis, not as part of a layered routine.
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