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Pathways for the catabolism of caffeine have also been studied, although there are currently no reports of enzymatic and genetic studies having been successfully carried out.
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More rarely, social, economic and cultural factors were studied although there is some evidence that these factors have a potential influence on caregiving consequences.
This can provide an estimate of the impact of dissolved or desorbed molecules on the toxicological end points being studied, although there may be some adsorption of impurities to the filtration system which could lead to an underestimation of their impact.
Furthermore the finite element approximation of optimal control problem governed by hyperbolic integro-differential equations has not been studied yet, although there exists much research on the finite element approximation of hyperbolic integro-differential equations, see, e.g.[18], [19].
This has not been studied systematically, although there are reports of its success.
Its skeleton has been studied extensively, and although there are several limitations to its similarity to the human condition, these can be overcome through detailed knowledge of its specific traits or with certain techniques.
Other phthalates and their metabolites have been studied less frequently, although there is also evidence that they may be capable of inducing oxidative stress (O'Brien et al. 2001; Zhou et al. 2010).
The association between symptomatic hand osteoarthritis and disability in everyday life has not been studied in detail, although there is evidence that older people with hand problems suffer significant pain and disability.
In addition, since it was first identified, the role of Cx43 and gap junctions in regulating malignant phenotype has been widely studied, although there are still several aspects of this process that remain elusive.
In particular, the potentially different role of the immune response in squamous versus adenocarcinoma has not been thoroughly studied, although there are indications for differences between the subtypes [ 24].
The prevention of acute and delayed CINV for intravenous agents and one day regimens is well studied, although, there are few data about management of CINV induced by oral cytotoxic agents and targeted therapies, usually administered in extended regimens of daily oral use.
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