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In contrast, the rapid and transient induction of miR-9, miR-146a and miR-155 has been speculated to negatively regulate the acute responses following activation of innate immune through down-regulation of proteins involved in the receptor-induced signalling pathways.
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This thin layer was speculated to be natural tungsten oxide.
It may be speculated that subclinical macroangiopathy negatively impacts the brain in T1DM, and that it may aggravate the effect of proliferative retinopathy on the brain.
Since such a population was found in HY TCR transgenic males (where HY-specific T cells are negatively selected) it was speculated that these cells might be escapees from negative selection [31].
It can be speculated that previous unsuccessful attempts at losing weight can negatively affect patients' confidence in the possibility to treat obesity effectively, thus making the psychological burden heavier and heavier.
Since smoking affects periodontal health negatively [ 33], it can be speculated that the true difference in periodontal conditions between the psoriasis and control groups could be overestimated to some extent.
Therefore, it may be speculated that a decline in the provision of glucose to a child's brain, for example 2 3 h following a high-GL meal, may negatively impact on neural functioning.
And that's speculating.
But I am speculating here.
He knows he's speculating".
A decrease in PGI activity has previously been shown to negatively impact xylose uptake (Jeppsson et al. 2002) and it was then speculated that the decreased NADPH, arising from low G6P being channeled to the oxidative branch of the pentose phosphate pathway (PPP) (Fig. 1), directly affected the NADPH-dependent xylose reduction to xylitol by xylose reductase (XR).
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