Sentence examples for been speculated to alter from inspiring English sources

The presence of an expanded polyQ stretch has further been speculated to alter the Htt structure, thereby leading to its cytotoxicity.

This mutant showed hyperphosphorylated Sir2 in Figure 2G, and this was speculated to alter Sir2 deacetylation activity.

ED has been speculated to be a key element in body-weight regulation because it may alter appetite control signals (i.e. hunger and satiety).

It would be interesting to investigate whether JNK signalling is altered in loss-of-function mouse models where alterations in synaptic activity have been speculated to be a possible root cause of Batten's disease.

In advanced lung cancer, phase angle was speculated to be an indicator of altered tissue electrical properties [ 34].

Altering the composition of the LCFA in the feed can hence be speculated to cause most pronounced changes in the regions where these fatty acids are mainly absorbed.

This thin layer was speculated to be natural tungsten oxide.

Importantly, due to changes in oral absorption, decreased protein binding of drugs, and renal insufficiency with impaired drug clearance, it has been speculated that diabetes might alter the pharmacokinetics of antimicrobial drugs, which could lead to treatment failure or resistance (33).

Coliform bacteria have also been found more abundantly in colicky infants and it is speculated that altering the intestinal microbiota composition may positively influence the management of affected infants [ 19].

Of note, phosphorylation of these sites has been demonstrated to reduce SOS1's binding affinity for GRB2, and it could be speculated that mutations altering the recognition motif at these sites might affect phosphorylation and promote enhanced GRB2 binding.

For example, it was also shown that the P112Q TRPC6 mutant was more highly expressed at the cell surface and it was speculated that the altered subcellular trafficking could explain the enhanced channel activity [9], [17].