It has been speculated that up-regulation of the ECM due to local thinning within the ECM can lower any stiffness that may occur.
It can therefore be speculated that up-regulation of pro- (e.g. VCAM-1, ICAM-1, ET-1 and ROS) and anti-atherogenic (e.g. eNOS) genes differ when the pressure stimulus involves chronic elevation compared with the transient, episodic and cyclical increases in blood pressure which occur in response to exercise [ 97, 98].
In hypoxic situations, α-enolase also acts as a stress protein and it has been speculated that its up-regulation may provide protection to cells by increasing anaerobic metabolism [3].
Here is what I am speculating: That opening up the mouth, chest cavity (through slow, deep breathing) and orgasmic capacities via the vagus nerve may lead to powerful orgasms and possibly multiples and female ejaculation.
It's been speculated that UPS may pick up the bulk of DHL's domestic shipments to the tune of $1 billion per year in additional revenue – good news for UPS, who had a rough third quarter.
It has been speculated that the remaining compensation, up to two-fold, could be mediated by a more general buffering mechanism acting on all genomic regions that are present in single copy [ 16- 19].
It has been speculated that the agreement could be worth $40m and involve up to 100 refugees.
It has been speculated that self-styled "perpetual backpacker" Emil Kaminski, 33, led the group of tourists up the mountain.
It could be speculated that if mortality during follow-up differed between the two groups, then a potential effect of the intervention on growth could be masked, but there was no strong difference in mortality between the VAS and placebo groups.
In 2006, global aged population (≥ 60 years) numbered 700 million, and it is speculated that by 2050, this number would rise up to 2 billion.
It can be speculated that because AGEs promote inflammation, early build-up of AGE stores may start undermining innate defenses from childhood.
