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Although it has been speculated that plasma membrane permeabilization by chitosan in bacteria and fungi is associated with the interaction between the positive amino groups of chitosan and the negative charges of phospholipids, no conclusive data are available [ 10, 12, 18].
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It has been speculated that PKC helps to recruit ADAMs to specific sites on the plasma membrane, and upon phosphorylation/activation of the ADAMs, EGFR ligands shedding occurs.
Because these molecules are plasma membrane-associated and involved in mitogenesis, it has been speculated that they function in concert with one another to promote breast cancer development and progression.
It has been speculated that NH3 could be the chemical species that enters the plant from the external medium via the plasma membrane [ 7, 16].
It has been speculated that scar formation leads to tape shortening and stiffening.
In an animal study with normal, wild-type mice, it was speculated that elevated plasma PS concentrations after PS feeding could be atherogenic because these concentrations were correlated with impaired endothelial vasorelaxation in situ (25).
It is speculated that one of reasons that plasma antioxidant increase with aging was due to the lipid peroxide increase with aging.
In addition, it is speculated that STIM1 in the plasma membrane may mediate cell-cell interactions through its extracellular facing N-terminal domain [32], [33].
It could be speculated that the complexes in plasma are not necessarily related to those detected in tumor tissue.
The exact antimigraine mechanism of sumatriptan remains unknown; thus, it could be speculated that a reduction in PACAP38 plasma levels might play a role.
Indeed, it was speculated that the differential evolution of plasma IgG1 and IgG3 antibodies resulted from a different catabolism and/or use of these antibodies [32].
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