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It has long been speculated that molecular chaperones are able to accelerate the evolutionary rate of their clients under the direct buffering hypothesis (Bogumil and Dagan 2010; Lachowiec et al. 2013).
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It may thus be speculated that molecular vibrations affect the structure of the cytoskeleton as a component of symmetry breaking, and could impact the delivery of molecular cargo by increasing the thermal energy of the cytoskeletal components.
But it has been speculated that due to its molecular weight it is expected to be filtered through the glomerulus but not through low-flux hemodialysis membranes; so dialysis clearance can not be the reason of lower levels in HD patients [ 25].
Primary cilia are increasingly being recognized as cellular 'antennae' which sense and transduce signals from the microenvironment, particularly through Wnt and Sonic hedgehog signaling, and based on previous studies in Xenopus and zebrafish, it has been speculated that cilia can function as molecular switches between canonical and non-canonical signaling pathways [ 34, 35].
Indeed, it has been speculated that the C. jejuni-induced neuropathies are probably related to the molecular mimicry between gangliosides in nerve tissue and LOS on the C. jejuni cell surface [7].
Although it has been speculated that alternative HER receptor activation mediates resistance to targeted therapies, this is the first time that a molecular mechanism is provided to explain drug resistance in breast cancer cell lines.
It has been speculated that BUBR1 antagonizes Aurora B at the kinetochore to promote chromosome alignment at the metaphase plate, but the molecular mechanism has remained unknown.
It has been speculated that scar formation leads to tape shortening and stiffening.
It is speculated that Hsp90 as molecular chaperones play an important role in signal transduction and stress management in C. nankinginse.
It is speculated that the first and seventh cysteines of the LMW-GS form the inter-molecular disulfide bond, while the rest form three intra-molecular disulfide bonds [ 30, 31].
Based on this difference in color, it is speculated that TX-cut does not react further with the polyaldol species and thus does not increase the molecular weight further like the PyGas wash does.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com