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2 In familial RCC, as well as in sporadic ccRCC, it is common that one VHL allele is deleted, whereas the remaining allele has acquired an inactivating aberration rendering a complete loss of functional protein. 1 It has been speculated that additional tumor suppressors are present on chromosome 3p as loss of this arm is a frequent event in ccRCC and other tumors.
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It is speculated that additional genomic alteration(s) are required for the pathophysiology of PTCL having STX11 alteration.
In fact, it can be speculated that additional factors may have contributed to the observed resistance training effects.
With the use of an adjuvant-free protocol, it is speculated that additional danger signals, such as LPS content in the OVA preparation, may be required to facilitate the sensitization process [ 36].
In addition, it has been speculated that there are many additional types of ncRNA that have yet to be discovered.
In contrast, it has been speculated that increased IL-1Ra could have an additional metabolic effect that leads to insulin resistance.
In addition, it has been speculated that the septin filaments may serve as scaffolds for the recruitment of additional proteins.
It's been speculated that UPS may pick up the bulk of DHL's domestic shipments to the tune of $1 billion per year in additional revenue – good news for UPS, who had a rough third quarter.
It may be speculated that the additional electron acceptors, being in proximity to one belonging to light absorbing chromophore, causes an additional increase of electron affinity of the electron-accepting moiety of light absorbing chromophore.
It could be speculated that the additional amount of energy provided by the collagen peptides may be responsible for the respective effects.
Because H2O2 could rapidly induce transient phosphorylation of Akt and ERK1/2, it was speculated that the additional generation of H2O2 was involved in partial activation of Akt and ERK1/2.
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CEO of Professional Science Editing for Scientists @ prosciediting.com