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Warkentin 4-T score should be used to assess the probability of HIT, even though it has not been specifically validated in intensive care (see Additional file 3) (strong agreement). .
However, this formula has not been specifically validated in patients with diabetes [ 36].
13 Second, ECG coding for CAD based on Minnesota coding has not been specifically validated in Indo-Pakistani populations.
41 Although this instrument has not been specifically validated in Moroccan-Dutch participants, the sample in which it was studied in the previous research was ethnically diverse.
Acute physiology and chronic health evaluation (APACHE) II [ 37] and SAPS II [ 38] scores have been specifically validated in certain groups of critically ill cancer patients.
Warkentin 4-T score should be used to assess the probability of HIT, even though it has not been specifically validated in intensive care (see Additional file 3) (strong agreement).
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Associations found in one ethnicity cannot be generalized across all ethnicities, meaning that findings in one population need to be specifically validated in another.
Second, the hair biomarker was specifically validated in a Yup'ik population ages 14 79 years [ 46], which does not cover the younger age range of participants in our study.
All but one study (29) reported use of a validated physical activity questionnaire to assess exposure, although only one of these questionnaires was specifically validated in pregnant women, with satisfactory results (24).
The dried blood spot method has been used extensively in South African populations over the past few years but has not been specifically validated for South Africa.
While our pragmatic approach may have resulted in false-positive cases, the accuracy of CD recording in primary care was specifically validated against medical records 28 in a small sample of patients, showing a good concordance between paper and electronic records.
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