Sentence examples for been solved to date from inspiring English sources

But checkers — or draughts, as it is known in Britain — is the most complex game that has been solved to date, with some 500 billion billion possible board positions, compared with the 765 possibilities in tic-tac-toe.

To our knowledge, this numerical problem has not been solved to date, thus, these extreme pressure conditions are still out of numerical reach even though the researchers are on track to address this problem for extra deep reservoirs (Zhang et al. 2011).

As no inhibitor-mtFabH co-crystal structures have been solved to date, we investigated the binding pattern of TLM with the closely related analogue ecFabB from E.coli [25].

The homology model generated for Mt-PrsA contains many structural features of other pRpp synthetases that have been solved to date.

In contrast to each of the structures of cis-AT PKS DHs that have been solved to date, PksEI14 crystallized as a monomer.

Although many protein structures have been solved to date, these only account for some 3% of all possible protein targets (TargetDB, 2010), with membrane protein structures being particularly challenging (Caffrey, 2003) and underrepresented (Doerr, 2008).

Independent of HHpred, multiple independent structural prediction engines suggested DENN as a possible homologue of C9ORF72, despite only two DENN structures being solved to date.

However, major problems caused by development of non-embryogenic cell lines, absence of a maturation phase and occurrence of malformed embryos could not be solved to date [ 25, 26].

First, the planning problem is solved to give the date of surgery for each patient, allowing for the availability of operating rooms and surgeons.

For each sampling date, the system was solved to calculate the concentration of malate in the pulp, using the "nleqslv" function of the R software, which solves a system of non-linear equations using a Broyden method (http://cran.r-project.org/web/packages/nleqslv/index.html).html

The only Millennium Prize Problem solved to date is the Poincaré conjecture, which is not easily explained as an aside in an article about a different mathematics concept.