Moreover, the synonymous variant (PLD3 p.Ala442Ala; rs4819) that had been significantly associated with LOAD in the original publication11 did not show association with the AD phenotype in our sample in either LOAD or EOAD cases (Table 1).
High resilience has also been significantly associated with positive outcomes, including successful aging, lower depression, and longevity.
K-ras mutations have been significantly associated with a lack of response to EGF-R tyrosine kinase inhibitors in patients with NSCLC and with a lack of response to cetuximab or to panitumumab in patients with advanced colorectal cancer.
Hippocampal atrophy has been significantly associated with memory impairment, a characteristic of AD.
Greater duration of muscle co-activation of bi-articular leg muscles during stance has also been significantly associated with better RE [201].
This possibility is further supported given that motivation to not be withheld from competition has been significantly associated with underreporting of concussion [57].
Likewise, DNA methylation has been significantly associated with baseline HbF [38, 46, 47] but provided no substantial explanation for HbF induction in response to HU.
AKI has been significantly associated with increased short-term mortality [3, 4, 6, 8], but results about its impact on increased long-term mortality among initial survivors of AKI and critical illness are few and conflicting.
For example, smoking is a major risk factor for a series of medical disorders (Ezzati et al. 2002), and has been significantly associated with child abuse but not child neglect (Norman et al. 2012).
Additionally, symptoms of depression, measured via the CES-D, have been significantly associated with current smoking status and difficulty quitting among Hispanics and in the general population [35 37].
Youth's desire to look like females in popular media has already been significantly associated with tanning bed use.
