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Thus far, these mammalian cellular and viral IRES elements have not been shown to function in the yeast Saccharomyces cerevisiae.
No natural or engineered Cas9 variants that have been shown to function efficiently in mammalian cells offer a PAM less restrictive than NGG.
It has been shown to function as an osmolyte and lipotrope, preventing accumulation of lipids in the liver and probably protecting against oxidative stress.
The product of the c-myb proto-oncogene is a highly conserved transcription factor that has been shown to function as both a transactivator and repressor.
miRNAs have been shown to function as regulatory molecules and to play an important role in cancer progression.
Genetically engineered toxoids have been shown to function as potential vaccine candidates in the prevention of Clostridium derived infectious diseases.
Recently endogenous small RNAs (sRNAs) of various biogenetic origins have been shown to function non-cell-autonomously.
Cannabinoids have been shown to function as protective agents via receptor-independent and/or receptor-dependent mechanisms against stressful conditions.
Birdsong and territorial behaviour have also been shown to function as paternity protection, although these behaviours have other primary functions.
The EFS has been shown to function for several commercial alloys, as well as in different environments.
Cardiac tissue has been shown to function as an electrical syncytium in both intracellular and extracellular (interstitial) domains.
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