To date, no single polymerase or amplification method has been shown to efficiently amplify both extremes of base composition with equal and optimum efficiency.
Among clay-size minerals, phyllosilicates (clay minerals) have been shown to efficiently protect SOC.
Notably, ISCs have been shown to efficiently form intestinal tumors upon deletion of Apc24 and play a critical role in adenoma and cancer cell self-renewal25,26 self-renewal25,26
Vertical flow systems filled with porous medium have been shown to efficiently remove volatile organic contaminants (VOCs) from contaminated groundwater.
Level-crossing analog-to-digital converters (LC ADCs) have been considered in the literature and have been shown to efficiently sample certain classes of signals.
Trehalose has been shown to efficiently stabilize dehydrated enzymes, proteins and lipid membranes, as well as protect biological structures from damage during desiccation by replacing water.
Ascorbic acid has been shown to efficiently scavenge ROS, protect membrane lipids against peroxidation (Sies and Sathl 1995) and increase reduced glutathione (GSH) levels (Amari et al. 2008).
The monoclonal antibody (mAb) J591 is directed against an extracellular epitope of PSMA and has been shown to efficiently target disseminated disease including metastases in lymph nodes and bone.
An enamel matrix protein derivative (EMD; Emdogain, Straumann, Basel, Switzerland) has been used in periodontal regenerative procedures for over 20 years, and it has been shown to efficiently enhance the outcome of healing [11, 12].
LRRK2 has been shown to efficiently phosphorylate moesin at Thr 558, and a peptide, LRRKtide, derived from it [33].
siRNA-mediated depletion of the clathrin heavy chain (CHC) has been shown to efficiently block clathrin-mediated endocytosis [29].
