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CD44 has been shown to colocalise at the site of HIV budding from the cell membrane in T cell and monocyte cell lines [ 30, 31].
Protein phosphatase 2A has been shown to colocalise with β1-integrin, which is required for FAK regulation (Young et al, 2002, 2003).
Although it has not been reported to bind S100A6, lamin B has been shown to colocalise with S100A6 at focal points within the nucleus (Tomas and Moss, 2003).
Regarding the regulation of MMP gene expression, the oncogene Ras (which upregulates MMP-1 and cathepsins) has been shown to colocalise with cathepsin L in the vessels of the RA synovium [ 126].
Intriguingly, VAMP8-positive vesicles in macrophages of wildtype mice have recently been shown to colocalise with TNFα, and in the same study, TNFα release from macrophages was inhibited in VAMP8-deficient mice (Pushparaj et al., 2009).
We generated 3-66-66-GFP and expressed it in pex19Δ cells with either Pex3-mCherry or Pex22-mCherry, which has been shown to colocalise with Pex3 in the peroxisomal ER in pex19Δ cells (Halbach et al., 2009).
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Patches of crosslinked raft markers anchored in the exoplasmic plasma membrane leaflet were shown to colocalise with inner leaflet raft-associated Lck [ 11].
Recently, monocytic and cancer cells have been shown to produce actin rich protrusions which colocalise with matrix degradation and may be sites of MMP activity (Buccione et al., 2009; Linder, 2007).
CD9 has also been shown to exert an effect on EGFR, with complexes of CD9, EGFR, and β1 integrin colocalised in areas of cell cell interaction.
Survivin was recently shown to colocalise in the mitochondria, where it abolishes tumour cell apoptosis and promotes tumourigenesis in immunocompromised animals (Dohi et al, 2004).
In the other report, Sef was shown to immunoprecipitate and colocalise with the FGF receptor (FGFR) (Tsang et al, 2002).
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