Sentence examples for been shown that mutation from inspiring English sources
It has been shown that mutation of human SOS1 gene is responsible for a rare hereditary gingival fibromatosis type 1, a benign gingival overgrowth.
Prior to that it has already been shown that mutation of Ser57 and His355 completely abolished the enzymatic activity of HEF, essentially confirming the data from crystallography, but mutation of other residues in the vicinity, i.e. Asp247, Asn266 and His354 also affected the hydrolytic activity of HEF (Pleschka et al., 1995).
It has been shown that mutation at this particular site will reduce binding affinity by almost 4-fold [11].
It has also been shown that mutation in one of the ORFs in the flagellar operon region in X. oryzae leads to weak chemotaxis [ 49, 50].
However, it has already been shown that mutation of xanB results in an incapacity to produce symptoms and to colonize the sugarcane stalk [ 28].
It has also been shown that mutation in this gene appears to result in Sekiguchi lesion formations on rice leaves, and increased resistance to fungal infection [ 32, 33].
Recently, it has been shown that mutations in the signaling motifs indeed reduce or abolish AcrB activity (Liu and Zhang 2017).
Although it has been shown that mutations causing significant loss of pyrazinamidase activity significantly contribute to pyrazinamide resistance, the mechanism of resistance is not completely understood.
It has been shown that mutations in at least four myotubularin family genes (MTM1, MTMR1, 2 and 13) are causative for human neuromuscular disorders.
Finally, it has recently been shown that mutations in either ELG1 or CTF18 have the same effect in suppressing the hst3 hst4 mutant that contains hyperacetylated histone H3 at position K56 [38].
