It has been shown that modification of the cell surface with adhesion ligands is a viable approach to improve cell homing, yet current methods including genetic modification suffer potential safety concerns, are practically complex and are unable to accommodate a wide variety of homing ligands or are not amendable to multiple cell types.
Previously it has been shown that modification of the membrane dipole potential, through manipulation of sterol concentrations, can influence the activity of P-gp [29].
It has been shown that modification of virus capsids by PEGylation can significantly dampen the T-cell mediated immune response against the virus and stimulate the antibody response against a secreted antigen [26], [27], [30], [54].
It has been shown that modification of solutions or other conditions during the reperfusion phase can alter the extent of cellular and functional damage to the myocardium.
It has been shown that modification of intracellular proteins by hydroxynonenal and malondialdehyde leads to alterations of intermolecular interactions and biochemical functions [9,10,23,29,67 70].
It has been shown that modification to this residue has no effect on the structure of tUIM or the interaction between tUIM and K63-Ub2 (Setiyala et al., 2012).
Importantly, it has been shown that modification of LPG during metacyclogenesis facilitates detachment of Leishmania major from the midgut in the sand fly species, Phlebotomus papatasi, and is essential for vector transmission (Sacks and Kamhawi, 2001; Kamhawi, 2006).
In this work, it was shown that modification of the surface of pH-sensitive field-effect transistors with zeolites can improve some characteristics of biosensors.
