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It has been shown that modest PGC-1α expression in skeletal muscle increased insulin sensitivity [46] whereas excessive PGC-1α expression in transgenic mice rendered skeletal muscle resistant to insulin [35].
It has been shown that modest changes in lifestyle can delay or even prevent the onset of diabetes in high risk populations [ 17].
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The collection is being lauded by fashion magazines and websites because the designers are showing that "modest" doesn't have to equate to dowdy, boring or head-to-toe neutrals.
It has been shown that even modest degrees of acute renal failure without need for haemodialysis increase the risk for death by fivefold [ 7].
On the other hand, it has been shown that a modest level of PGC-1α overexpression in skeletal muscle can increase insulin sensitivity (Benton et al., 2008) and that it protects against muscle loss and metabolic dysfunction upon aging (Wenz et al., 2009).
It has been shown that there is only a modest relation between reported vitamin D intake from an extensive dietary questionnaire and serum levels of 25-OHD3 [ 30].
However, it has also been shown that while treatment effects are modest overall regardless of initial therapy, some nonresponders to one treatment may still be responsive to an alternative medication.
Previously, it has been shown that a deletion of SGS1 causes a modest yet significant increase in homologous recombination [10], [54], [56].
It is shown that even with modest device technology (e.g., turbine inlet temperature of 1650 K), maximum efficiency above 50% can be achieved in simple-cycle engines.
On average while computing arrangements with few degeneracies (on sample molecular models), it is shown that certifying the result incurs a modest factor of two with respect to calculations using a plain double arithmetic.
It is shown that the radial flow geometry leads to modest pressure drop.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com