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To that end, it has been shown that induction of autophagy results in selective degradation of catalase, leading to accumulation of mitochondrial ROS and ultimately cell death[27].
More recently, it has been shown that induction of autophagy also protects RA synovial fibroblasts from ER stress [ 9].
It has been shown that induction of fluoroquinolone resistance during treatment was also well recognized and had been reported [ 102, 103].
It has been shown that induction of apoptosis by HHT in combination with TRAIL reduced the growth of tumor xenotransplants (HT-29) in immunodeficient mice within the therapeutic window [ 30].
Interestingly, expression of several CT antigens, including GAGE, can be induced by the hypomethylating agent 5-aza-2′-deoxycytidine (Sigalotti et al, 2002), and it has been shown that induction of transcription correlates with hypomethylation of CT antigen promoters (Janssen et al, 1999; De Smet et al, 2004).
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It is shown that induction heating at a frequency of about 400 kHz is suitable for tests of parts with thermal barrier coatings (TBC).
Recently it was shown that induction of heme oxygenase-1 may reduce ischemia/reperfusion injury, probably by enhancing microvascular blood flow [ 15].
Using a stochastic model, it was shown that induction therapy would have to last at least 180 days for cocktails containing two RTI-like drugs and a PI-like drug [ 20, 21].
In support of the role of caspase-independent cell death mediated by vitamin D, it was shown that induction of apoptosis in MCF-7 cells was correlated with disruption of mitochondrial function, which was associated with Bax translocation from the cytosol to the mitochondria, cytochrome C release and production of reactive oxygen species.
It was showed that induction of the protein in tolerant barley genotypes may alleviate water-deficit stress by increasing ATP supply to meet increased stress-related energy demand [ 27].
Recently, it has been shown that the induction of recA in irradiated D. radiodurans is regulated by the IrrE/PprI protein [108], [109], which consists of two domains, a Xre-like HTH domain and a Zn-dependent protease.
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