Sentence examples for been shown that hypoxic from inspiring English sources

Recently, it has been shown that hypoxic stress can enhance the release of endothelial progenitors from the bone marrow and their recruitment and incorporation into tumor vasculature [30].

It has been shown that hypoxic gradients regulate CXCL12 through HIF induction (Ceradini et al, 2004).

It has been shown that hypoxic cells use glutamine as a major substrate for lipid synthesis (Metallo et al., 2012; Wise et al., 2011).

It has been shown that hypoxic conditions may slow down the growth rate of tumours but can promote the onset of an EMT leading to invasion (Yang et al, 2008).

For example, it has been shown that hypoxic cells can be targeted by combining a HIF-responsive promoter with an oncovirus that is armed with the interleukin-4 gene.

Across a range of oxygen tensions and mammalian cell lines (including human tumour and endothelial cells) it was shown that hypoxic cells could be transfected.

It has been shown that under hypoxic conditions nitrite-derived NO, inhibits complex I, but ameliorates oxidative inactivation of complexes II-IV and aconitase during reoxygenation, thus preventing mitochondrial permeability transition pore opening and cytochrome c release [168].

Additionally, it has been shown that under hypoxic conditions, HSF is actively transcribed by HIF due to the presence of two HRE sequences on intronic region of HSF gene [65].

Additionally, it has been shown that under hypoxic conditions different concentrations of NO as an inhibitor of the mitochondrial cytochrome c oxidase have different effects on HIF- α stabilization.

It has been shown that under hypoxic conditions nitrite-derived NO, inhibits complex I, but ameliorates oxidative inactivation of complexes II-IV and aconitase during reoxygenation, thus preventing mitochondrial permeability transition pore opening and cytochrome c release [ 168].

In yeast, it has been shown that COX5b, the hypoxic isoform of COX5, is more efficient at pumping protons across the inner mitochondrial membrane (i.e., requires less energy to pump the same number of protons), thereby producing a stable membrane potential and ATP concentration despite utilizing fewer oxygen molecules.