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It has been shown that development of specific cell lineages is often dependent on specific miRNAs.
Further, it has been shown that development of antibody might take more than seven days in some patients.
It has also been shown that development of TH17 lymphocytes in the intestine is stimulated by microbiota-induced IL-1β (but not IL-6) production [ 93].
It has been shown that development of adalimumab antidrug antibodies are associated with lower response and remission rates, while the clinical importance of etanercept antidrug antibodies is less clear.
However, it has been shown that development of AD pathology is associated with a 1.5-fold or more increase of expression of APP in Down's syndrome patients [ 51, 60] and a twofold increase in patients with APP gene duplication [ 15, 26, 36, 49, 50, 55].
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It is shown that development of a sub Raleigh shear crack is connected with a vortex traveling ahead of the crack tip at a shear wave velocity.
It is shown that development of an instability responsible for the substorm expansion phase onset takes place in the regions of low β or at the boundary of the regions of high and low β.
It is shown that development of a special combustion device with high conversion level of fuel chemical energy to useful radiant energy is required, to improve further the system efficiency.
Furthermore, research questions are shown that are relevant for the development of such a tool and a suitable research methodology is suggested.
It is shown that process intensification is fully in development and, as a consequence, the essential characteristics are subject to debate.
Interestingly, it has been shown that cancer development is correlated with the development of type II diabetes by the common alteration of the insulin-like growth factor 1 receptor signaling pathway, which is sensitive to insulin resistance and affects growth and differentiation of cancer cells [ 88].
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