Sentence examples for been shown in mammalian from inspiring English sources

On the basis of their highly conserved sequence, histone variants have been assumed critical for the function of mammalian chromatin; however, a requirement for a histone variant has not been shown in mammalian cells.

Earlier, it has been shown in mammalian cells that protein synthesis slows down when cells are in the G2/M stage of the cell-cycle [50].

Thirdly, it has been shown in mammalian muscle that during isotonic contractions at high speeds of muscle contractions, slow-twitch muscles are less efficient in doing external work than fast muscles [3].

Furthermore, analogous to what had been shown in mammalian cells [ 17], AA2 was also functional as an intrabody and labeled Golgi stacks in living Drosophila S2 cells.

In recent years the importance of functional genomic approaches to simultaneously analyze the transcriptional modulation of thousands of genes in response to radiation has been shown in mammalian cells (3 6).

A conserved cysteine close to the end of helix IV has been shown in mammalian S100A10 and A11 to stabilize the dimer by intermolecular disulfide bridge formation [ 26, 27].

Although microinjection of the 20-nt sgRNA results in the greatest proportion of recombinants with respect to transgenic animals obtained (32%), the remaining sgRNAs also can form functional complexes with Cas9 (13% and 4% recombinants, respectively; Table S2), as was shown in mammalian systems (Qi et al. 2013; Ran et al. 2013).

However, four centrioles have never been shown in any mammalian zygotes; only three centrioles were observed1,;2.

However, it has been shown in zebrafish, mammalian and D. melanogaster cells that blocking translation initiation on reporter mRNAs by interfering with either 40S recruitment [39], [42], 5' UTR scanning [40], or start codon recognition [38] does not prevent miRNA-mediated deadenylation.

In addition, enrichment of H3K27me3 has not been shown in other mammalian species to be mutually exclusive with the MOAs used in this study.

Investigating changes in body weight through life could also uncover declines in body weight with age that are potentially linked to senescence, as has been shown in several mammalian species [ 32– 32].