It has been shown before that SLNs can pass the BBB efficiently [23].
It has been shown before that patients with ICA occlusion and a compromised flow state of the brain may improve spontaneously over time [25].
It has been shown before that different designs of orchard sprayers result in different airflow profiles, but it is still unclear whether these differences strongly affect on-target spray distribution, and what is the role of tree architecture.
It has been shown before that entries in miRBase are questionable and the chance of incorporating a large share of low-quality hairpins increases with the number of hairpins available when using MCCV.
It has been shown before that "lesser mobilization of older parents [with younger children] is linked to worsening living conditions, themselves due to unemployment or illness, a less favourable local context due to suburban decay.
Indeed, it has been shown before that face-selective regions are biased to process foveal stimuli during free-viewing [19].
It has been shown before that inflammatory mediators can affect lipid metabolism (reviewed by Khovidhunkit et al. [27]).
It had been shown before that SH3 domains bind to proline-rich sequences (PxxP) of partner molecules acting downstream in a signaling hierarchy [25], [42].
It has been shown before that so called targeted layered containment strategies, a combination of antiviral prophylaxis and non-pharmaceutical interventions, can be effective in reducing the transmission of pandemic influenza [8].
Although it has been shown before that LPS increases μ opioid receptor expression in the rat mesenteries [64], to our knowledge our results demonstrate for the first time that μ opioid receptor surface expression on neutrophils is increased after stimulation with LPS.
We have previously shown that placental infection with P. falciparum affects Th1 differentiation of cord blood T lymphocytes [24] and it has been shown before that malaria infection can suppress immunity to a variety of viral infections, such as HIV, Epstein Barr virus, vaccinia and lymphocytic choriomeningitis virus [25], [26], [27].
