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Given that the anterior insular has been robustly implicated in interoception (Craig 2009; Critchley et al., 2004), it is plausible that previous findings of insular activation on the UG might reflect the general representation of bodily responses (see also Kirk, Downar and Montague 2011), as opposed to activation of distinct negative affective states such as disgust or anger (Sanfey et al., 2003).
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An association between PD and MAPT and the surrounding 17q21 locus results from an ancient paracentric inversion and was robustly implicated in clinical PD and in autopsy-confirmed series of PD in Caucasian populations [ 40- 42].
In this context it is interesting to note that one of the cis acting candidates at the chromosome 8 locus is Fto, a gene that has been robustly validated for association with human obesity [36] [38] and has recently been implicated in regulating energy expenditure in mice [39].
Some interesting genes have been implicated, but no variants have yet been robustly and reliably linked to response.
The recurrent identification of POGZ in these studies has robustly implicated POGZ in diverse NDDs, yet no thorough clinical analysis for POGZ variant-associated phenotypic features has been published to date.
Strikingly, the most robustly overrepresented motifs in our set match E- and D-boxes, the elements that have previously been implicated in the light response of the period2 gene [25].
McDowell has been implicated in that dispute.
Military men have been implicated in her killing.
Calcium signaling has been implicated in plant graviperception.
The drug has been implicated in botched executions in Ohio, Arizona and Oklahoma.
APHs have been implicated in antibiotic resistance.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com