There is considerable potential in linking databases that have previously been considered too sensitive for record linkage or where linkage is restricted by data protection legislation [ 48].
The study of reaction-system topology (the set of all participating reactions) has long been restricted, by lack of data, to small subsystems.
Data has been restricted by being behind computers and screens but once it becomes endemic across the real world, people might say, 'well, this is the new normal'".
Although generalized linear mixed modeling would be an excellent alternative, such analysis was restricted by the data structure (complexity due to multiple intrinsic hemodynamic and scan parameters) of the present study [24].
We concluded that research using many of the identified renal registries with high-quality information would be restricted by both limited data collection and dissemination as well as access to external researchers.
As a practical limitation, the choice of M may be restricted by the available data.
However, we were restricted by the available data as many samples (170) in our datasets were surrounding tissue (N), and only 60 samples were healthy tissue samples (H).
The analyses in this paper were restricted by the available data, and conformed to WHO-defined age groups and cause categories.
The explorative analyses were limited by the routine data available about these events; the detection of epidemics other than measles was restricted by the limited diagnostic data collected at the paediatric ward.
An additional limitation of case-linkage is that data interpretation is restricted by the accuracy and completeness of data available.
