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Evidence that doesn't come from extreme populations usually comes from animals – the often-quoted idea that early experiences can affect the brain-wiring process, altering the final number of synapses by as much as 25%, comes from a rat study and has never been reproduced in humans.
The effects of administration of PACAP on sleep in humans has not been extensively studied and the PACAP-effects observed in animals (increase in REM-sleep) [97] have so far not been reproduced in humans under the described conditions.
The effects of GLP-1 receptor agonists on vasodilation, blood pressure and triglyceride concentration have been reproduced in humans with native GLP-1 and different GLP-1 receptor agonists.
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In the late eighties, Dr. Anton Wernig, a neurophysiologist at the University of Bonn, in Germany, decided to find out if Edgerton's results with cats could be reproduced in humans.
However, comparatively few clinical studies have been carried out to evaluate whether the positive results obtained in animals can be reproduced in humans.
The study was not designed to test whether the changes in glucose metabolism observed in the rat could be reproduced in humans.
However, for the latter disease, the results could not be reproduced in humans.
Although the impact of miR-467b-5p miR-467b-5p miR-467b-5p in humans, our findings showouldt such a mechanotm is possibee in the hippocampus and could involve othereproducedsensinive miRNAs.
Most importantly, whenever possible we should collect tissue samples post-chemotherapy to address whether the findings by Jackson and colleagues in their mouse model could be reproduced in humans and correlate potential findings to TP53 status, anti-tumour response and long-term survival.
If the feat can be reproduced in human cells, it could provide a renewable source of human eggs or sperm for research.
If these findings are reproduced in human tumours, they would have important implications on surgical technique and subsequent marker measurement.
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