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Because CD44 has many variants that have been reported with distinct biological functions, we divided the studies into the anti-pan-CD44 and anti-CD44-v6 subgroups, which were the major antibodies applied in these studies, for each organ.
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So far, three kinds of cell-in-cell death have been reported with shared and distinct characteristics, including cannibalism, entosis and apoptotic cell-in-cell death.
The finding that the exons upstream of In100 are often skipped corroborates with the alternative splicing patterns observed for several caspase genes, including casp-2, 3, 8 and 9. Some of these splicing isoforms have been reported as distinct cDNAs with different biological activities [8], [9], [38] [40].
Individuals who suppress HIV-1 viral load to below detection limit have been reported as immunologically distinct from those with low level viraemia [4], [14], advocating the importance of viral load when defining patient groups.
To date nine distinct alpha subunits of VGSCs (Nav1.1 Nav1.9) have been reported, each with their own distinct expression pattern in the central (CNS) and peripheral (PNS) nervous systems.
The molecular-defined intrinsic breast cancer subtypes (luminal A, luminal B, HER2-enriched, basal-like, and normal-like) are typical examples, since they have been reported to be associated with distinct phenotype outcomes and have different chemotherapy responses and respective stratified therapy [ 4– 8].
Seasonal variation has been reported in the countries with distinct climatic seasons [ 24– 28], but its presence in Singapore is curious as this city state is located very close to equator and has little climatic variability across the year.
However, this broad classification fails to reveal the highly diverse nature of the Kv channels that underlie these currents, and in fact, a host of delayed rectifier and A-type K+ currents have been reported in arterial smooth muscle with distinct biophysical and pharmacological properties (9).
13 28 Recently, distinct psychopathological and personality traits have been reported in patients with PDS and EPS.
The second mutation, c.243G>A, p.Trp81X, has recently been reported in a family with PN that is distinct from the family in which we observe this change (22).
Tumours with defects on chromosome 8 have been reported in the literature as a distinct entity of breast tumours.
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