It has even been reported to trigger the mini-strokes known as transient ischemic attacks.
Although NPs have been reported to trigger PF development, its cellular and molecular mechanisms remain largely unclear.
ROS have been reported to trigger different pathological events due to oxidative stress including genotoxicity and fibrosis.
In many species, heat or cold stress has been reported to trigger pollen embryogenesis, the response being genotype dependent.
DENV has been reported to trigger a robust type I IFN response; however, IFN-α/β profile in the progression of disease is not well characterized.
Food protein-derived bioactive peptides (BPs) have been reported to trigger certain physiological responses in the body, thereby influencing health positively.
Moreover, inhibition of either PI3K or MAPK pathway has been reported to trigger each other's activity due to the presence of by-pass mechanisms in the form of positive or negative feedbacks as well as presence of proteins common to both pathways13,49,50.
Perhaps what is positively relevant to bone tissue engineering about copper is that this element has consistently been reported to trigger endothelial cells towards angiogenesis.
Chemokines such as MCP-1 has been reported to trigger integrin mediated firm adhesion and subsequent transmigration of monocytes [8].
During the last decade, FasL has been reported to trigger a RIP-dependent alternative form of cell death, exhibiting necrotic rather than apoptotic features [15].
In this respect, ROS of mitochondrial origin, depolarization of mitochondria and increased fission events each have been reported to trigger autophagic activity [41], [54].
